TaperMate

Mirtazapine liquid taper calculator

Dissolving a mirtazapine tablet in water lets you measure small doses with an oral syringe. Enter your numbers below to see how much of the liquid to take — and the formula so you can check it yourself.

Mirtazapine · liquid

Single dose calculator

mg
Strength of the tablet you're using.
mL
How much water you dissolve or disperse the tablet in.
mg
What you want to take today.
mL
Calculated for you.
Take this much of the liquid
2.5mL
from the 10 mL you mixed, to get a 12.5 mg dose.
Formula volume to take = (target dose ÷ tablet strength) × water volume
With your numbers (12.5 mg ÷ 50 mg) × 10 mL = 2.5 mL
Measure to the nearest 0.1 mL on your syringe.
Measure to nearest 0.1 mL
Standard oral syringes read to 0.1 mL. For very small volumes, ask your pharmacist about a 1 mL syringe.
Item 14L · Verify Validate this calculation
Tablet strength
50 mg per tablet (or part-tablet)
Water volume
10 mL
Target dose
12.5 mg — what you want to take
Volume to take
2.5 mL — from the 10 mL liquid
Check
50 × (2.5 ÷ 10) = 12.5 mg ✓
Every input and the formula are shown so you can verify the result by hand.
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Next step

Plan your full taper in TaperMate

This calculator handles one dose. The TaperMate app calculates a full reduction schedule with hold periods, microtapering and symptom monitoring — so each new dose is one tap away, not a daily maths problem.

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Example methodAdapted from the RELEASE Toolkit. Adjust the amounts to suit what your prescriber has agreed.

How to make a mirtazapine liquid

Dispersing a mirtazapine tablet in a known volume of water lets you measure a precise fraction with an oral syringe. The steps are the same whatever strength you make — adjust the tablet and water amounts to suit what your prescriber has agreed.

What you'll need

  • A pill cutter
  • Oral syringes — a 1 mL, 5 mL and 10 mL are useful
  • A small jar or glass for mixing
  • Drinking water at room temperature

Method

  1. Cut a mirtazapine tablet to the portion you need with the pill cutter.
  2. Crush the piece between two spoons over a small plate.
  3. Stir it into a measured volume of water in the jar to make a known concentration. Shake or stir to disperse.
  4. Stir again immediately before drawing your dose — the active ingredient settles quickly.
  5. Measure your prescribed dose with an oral syringe and take it.
  6. Make a fresh liquid each day and discard any unused liquid in the rubbish.

Tips

  • Many tablets disperse rather than truly dissolve, so the liquid will look cloudy — that is expected.
  • Use the smallest syringe that fits your dose; it is far more accurate for tiny amounts.
  • Keep the concentration the same each day so doses stay consistent.

When not to use this method

  • Modified-release formulations — crushing or dispersing destroys the release profile.
  • If your pharmacist has already dispensed a mirtazapine oral liquid, use that and enter its concentration into the pharmacy-liquid calculator instead.
  • If your prescriber has not discussed liquid tapering with you.

Sources to discuss with your prescriber